A Modern Approach to Classify Missense Mutations in Cardiac Channelopathy Genes

A modern approach to classify missense mutations in cardiac channelopathy genes.

A statistical approach to classify Skype traffic

Abstract- Skype is one of the most powerful and high-quality chat tools that allows its users to use of many services such as: transferring audio, sending messages, video conferencing and audio for free. Skype traffic has a lot of Internet traffic. Hence, Internet service providers need to identify traffic to do the quality of service and network management. On the other hand, Skype developers ...

Missense mutations in disease genes: a Bayesian approach to evaluate causality.

The problem of interpreting missense mutations of disease-causing genes is an increasingly important one. Because these point mutations result in alteration of only a single amino acid of the protein product, it is often unclear whether this change alone is sufficient to cause disease. We propose a Bayesian approach that utilizes genetic information on affected relatives in families ascertained...

Classification of Missense Mutations of Disease Genes.

Clinical management of individuals found to harbor a mutation at a known disease-susceptibility gene depends on accurate assessment of mutation-specific disease risk. For missense mutations (MMs)-mutations that lead to a single amino acid change in the protein coded by the gene-this poses a particularly challenging problem. Because it is not possible to predict the structural and functional cha...

a frame semantic approach to the study of translating cultural scripts in salingers franny and zooey

the frame semantic theory is a nascent approach in the area of translation studies which goes beyond the linguistic barriers and helps us to incorporate cognitive and cultural factors to the study of translation. based on rojos analytical model (2002b), which centered in the frames or knowledge structures activated in the text, the present research explores the various translation problems that...